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The 15 Highest Grossing Prescription Drugs In America

American patients spent $307 billion on prescription drugs in 2010, up 2.4% from the past year according to IMS Institute for Healthcare Informatics.

AstraZeneca's Crestor posted the biggest increase with $770 million in new sales.

Name brand medicine, however, have been losing out to generics. Generics now make up 78% of total prescriptions, up from 63% just four years ago.

Spending on Pfizer's Lipitor, America's highest-grossing drug, has dropped in each of the past five years. With a patent expiring in 2011 it will compete with new generics entering the market.

Seroquel, another top seller, will lose patent protection in 2012.

The 15 Highest Grossing Prescription Drugs In America
	Drug	Gross	5 Year Growth
1	Lipitor	$7.2 billion	-16 percent
2	Nexium	$6.1 billion	23.5 percent
3	Plavix	$6.1 billion	110.3 percent
4	Advair Diskus	$4.7 billion	20.5 percent
5	Abilify	$4.6 billion	142.1 percent
6	Seroquel	$4.4 billion	46.7 percent
7	Singulair	$4.1 billion	36.7 percent
8	Crestor	$3.8 billion	192.3 percent
9	Actos	$3.5 billion	34.6 percent
10	Epogen	$3.3 billion	3.1 percent
11	Remicade	$3.3 billion	32 percent
12	Enbrel	$3.3 billion	6.5 percent
13	Cymbalta	$3.2 billion	166.7 percent
14	Avastin	$3.1 billion	82.4 percent
15	Oxycontin	$3.0 billion	287.5 percent
Data: Business Insider

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The 15 Highest Grossing Prescription Drugs In America